View the complete publication list on PubMed: Dr. Hongchao Guo
2025
Sun T, Li Q, Geisinger JM, Hu SB, Fan B, Su S, Tsui W, Guo H, Ma J, Li JB. ADAR1 editing is necessary for only a small subset of cytosolic dsRNAs to evade MDA5-mediated autoimmunity. Nat Genet. 2025 Dec;57(12):3101-3111. Learn More
Weldy CS, Li Q, Monteiro JP, Peters TS, Guo H, Galls D, Gu W, Cheng PP, Ramste M, Li D, Palmisano BT, Sharma D, Worssam MD, Zhao Q, Bhate A, Kundu RK, Nguyen T, Mokry M, Miller CL, van der Laan SW, Li JB, Quertermous T. Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of the RNA sensor MDA5 in atherosclerosis. Nat Cardiovasc Res. 2025 Oct;4(10):1241-1257. Learn More
2024
Bi F, Gao C, Guo H. Epigenetic regulation of cardiovascular diseases induced by behavioral and environmental risk factors: Mechanistic, diagnostic, and therapeutic insights. FASEB Bioadv. 2024 Nov;6(11):477-502. PMID: 39512842. Learn More
2023
Guo H, et al. SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant. Sci Transl Med. 2023 Jan 25;15(680):eabp9952. PMID: 36696485. Learn More
2022
Wang YJ, Zhang X, Lam CK, Guo H, Wang C, Zhang S, Wu JC, Snyder M, Li J. Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome. Cell Syst. 2022 Nov 16;13(11):895-910.e4. PMID: 36167075. Learn More
2021
Guo H, Liu L, Nishiga M, Cong L, Wu JC. Deciphering pathogenicity of variants of uncertain significance with CRISPR-edited iPSCs. Trends Genet. 2021 Dec;37(12):1109-1123. PMID: 34509299. Learn More
2020
Wilson KD, et al. Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates. Dev Cell. 2020 Sep 28;54(6):694-709.e9. PMID: 32763147. Learn More
Ho H, Guo H, Means S, Tang J, Hunter P. Maternal Smoking Induced Cardiovascular Risks in Fetuses: How Can in silico Models Help? Front Bioeng Biotechnol. 2020;8:97. PMID: 32140462. Learn More
2019
Belbachir N, et al. RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome. Eur Heart J. 2019 Oct 1;40(37):3081-3094. PMID: 31114854. Learn More
Lee WH, et al. Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell-Derived Endothelial Cells. J Am Coll Cardiol. 2019 Jun 4;73(21):2722-2737. PMID: 31146818. Learn More
Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, Blau HM, Wu JC. A Human iPSC Double Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles. Cell Stem Cell. 2019 May 2;24(5):802-811.e5. PMID: 30880024. Learn More
Guo H, Tian L, Zhang JZ, Kitani T, Paik DT, Lee WH, Wu JC. Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development. Stem Cell Reports. 2019 Apr 9;12(4):772-786. PMID: 30827876. Learn More
2018
Nishiga M, Guo H, Wu JC. Induced pluripotent stem cells as a biopharmaceutical factory for extracellular vesicles. Eur Heart J. 2018 May 21;39(20):1848-1850. PMID: 29547885. Learn More
Zhang JZ, Guo H, Wu JC. Applications of genetically engineered human pluripotent stem cell reporters in cardiac stem cell biology. Curr Opin Biotechnol. 2018 Aug;52:66-73. PMID: 29579626. Learn More
Lee J, Shao NY, Paik DT, Wu H, Guo H, Termglinchan V, Churko JM, Kim Y, Kitani T, Zhao MT, Zhang Y, Wilson KD, Karakikes I, Snyder MP, Wu JC. SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation. Cell Stem Cell. 2018 Mar 1;22(3):428-444.e5. PMID: 29499155. Learn More
2016
Toh CX, Chan JW, Chong ZS, Wang HF, Guo HC, Satapathy S, Ma D, Goh GY, Khattar E, Yang L, Tergaonkar V, Chang YT, Collins JJ, Daley GQ, Wee KB, Farran CA, Li H, Lim YP, Bard FA, Loh YH. RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming. Cell Rep. 2016 Jun 21;15(12):2597-2607. PMID: 27292646. Learn More
Zhang W, Ni P, Mou C, Zhang Y, Guo H, Zhao T, Loh YH, Chen L. Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription. Sci Rep. 2016 May 26;6:26804. PMID: 27226076. Learn More
2015
Chen H, Guo R, Zhang Q, Guo H, Yang M, Wu Z, Gao S, Liu L, Chen L. Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E5936-E5943. PMID: 26483458. Learn More
Yang BX, El Farran CA, Guo HC, Yu T, Fang HT, Wang HF, Schlesinger S, Seah YF, Goh GY, Neo SP, Li Y, Lorincz MC, Tergaonkar V, Lim TM, Chen L, Gunarathne J, Collins JJ, Goff SP, Daley GQ, Li H, Bard FA, Loh YH. Systematic identification of factors for provirus silencing in embryonic stem cells. Cell. 2015 Sep 24;163(1):230-245. PMID: 26365490. Learn More
2012
Wu Z, Yang M, Liu H, Guo H, Wang Y, Cheng H, Chen L. Role of nuclear receptor coactivator 3 (Ncoa3) in pluripotency maintenance. J Biol Chem. 2012 Nov 2;287(45):38295-38304. PMID: 22977234. Learn More